›› 2011, Vol. 23 ›› Issue (3): 202-205.doi: 10.3969/j.issn.1004-616x.2011.03.010

• 论著 • Previous Articles     Next Articles

Semen quality and fertility analysis in HIV patients

HOU Zhi-wei，LI lian-bing，LU Jing，LI Xin-sheng，MA Ming-fu*   

  1. Science and Technology Research Institute of Population and Family Planning in Chongqing City, The Key Laboratory of Birth Defect and Reproductive Health, Chongqing 400020, China
  • Received:2010-12-24 Revised:2011-03-30 Online:2011-05-30 Published:2011-05-30
  • Contact: MA Ming-fu

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Abstract: To investigate the impact of HIV infection on semen quality and fertility. METHODS：Semen were collected from 5 healthy adult males and 23 HIV-infected males. Then routine semen parameters were measured by computer-assisted semen analysis system. Meanwhile，the influence of virus infection on the semen quality was analyzed. RESULTS：Comparing semen quality between healthy and HIV-infected adults，there was difference in sperm concentration，total sperm count，sperm vitality，sperm motility rate and sperm deformity rate (P＜0.01). The sperm concentration and total sperm count were 3 times lower in HIV-infected men. The sperm vitality and sperm motility were 3 fold more in healthy men. The sperm deformity was 2 fold more in HIV-infected men. The CD4+ T lymphocytes count in the semen from HIV-infected men was lower than that from healthy men，and there was significant correlation between CD4+ T lymphocytes count and sperm motility rate and sperm vitality ( r = 0.787 and 0.770，P＜0.01). CONCLUSION：HIV infection would seriously impact the semen quality and may decrease the fertility rate.

Key words: HIV, semen quality, fertility